SnapShot: CRISPR-RNA-guided adaptive immune systems.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 26406380.
- Also identified by DOI 10.1016/j.cell.2015.09.011 and PMC identifier 4668126.
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Abstract
Bacteria and archaea have evolved sophisticated adaptive immune systems that reply on CRISPR loci and a diverse cassette of Cas genes that are classified into three main types and at least eleven subtypes. All CRISPR-Cas immune systems operate through three main stages: acquisition, biogenesis, and interference. This SnapShot summarizes our current knowledge of these fascinating immune systems.
Medical subject headings
- Archaea
- Bacteria
- CRISPR-Cas Systems
- RNA, Guide, CRISPR-Cas Systems