Liposomal Bupivacaine: A Comparative Study of More Than 1000 Total Joint Arthroplasty Cases.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 26410636.
- Also identified by DOI 10.1016/j.ocl.2015.06.003.
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Abstract
Pain after total joint arthroplasty (TJA) can be severe and difficult to control. A single-dose local analgesic delivers bupivacaine in a liposomal time-release platform. In 2248 consecutive patients with hip and knee arthroplasty, half (Pre) were treated using a well-established multimodal analgesia, including periarticular injection (PAI), and half had the PAI substituted for a liposomal bupivacaine injection technique (Post). Pain scores were significantly lower for patients in the Post group for both hip and knee procedures. A large series of patients who had TJA experienced pain relief after the introduction of liposomal bupivacaine as part of an established multimodal protocol.
Medical subject headings
- Anesthetics, Local
- Arthroplasty, Replacement, Finger
- Arthroplasty, Replacement, Knee
- Bupivacaine
Anatomy
- knee