Clinical translation of a high-performance neural prosthesis.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 26413781.
- Also identified by DOI 10.1038/nm.3953 and PMC identifier 4805425.
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Abstract
Neural prostheses have the potential to improve the quality of life of individuals with paralysis by directly mapping neural activity to limb- and computer-control signals. We translated a neural prosthetic system previously developed in animal model studies for use by two individuals with amyotrophic lateral sclerosis who had intracortical microelectrode arrays placed in motor cortex. Measured more than 1 year after implant, the neural cursor-control system showed the highest published performance achieved by a person to date, more than double that of previous pilot clinical trial participants.
Medical subject headings
- Neural Prostheses
- Paralysis
- Translational Research, Biomedical