Acute Myeloid Leukemia Genetics: Risk Stratification and Implications for Therapy.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 26414465.
- Also identified by DOI 10.5858/arpa.2015-0203-RA.
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Abstract
Acute myeloid leukemia is a category of diseases with a common aggressive clinical presentation but with a prognosis and management that is dependent upon the underlying genetic characteristics of the neoplasm. The purpose of this brief review is to update the practicing pathologist on the current standard of care in the genetic evaluation of acute myeloid leukemia and to highlight future directions in the classification, genetic assessment, and management of these devastating diseases.
Medical subject headings
- Chromosome Deletion
- Leukemia, Myeloid
- Mutation
- Translocation, Genetic