Anticancer Platelet-Mimicking Nanovehicles.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26416431.
- Also identified by DOI 10.1002/adma.201503323 and PMC identifier 4998740.
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Abstract
A core-shell nanovehicle coated with a platelet membrane (PM) is developed for targeted and site-specific delivery of an extracellularly active drug and an intracellular functional small-molecular drug, leading to enhanced antitumor efficacy. This PM-coated nanovehicle can also effectively eliminate the circulating tumor cells in vivo and inhibit development of tumor metastasis.
Medical subject headings
- Antineoplastic Agents
- Biomimetic Materials
- Blood Platelets
- Drug Carriers
- Nanomedicine
- Nanostructures