A Self-Assembled Albumin-Based Nanoprobe for In Vivo Ratiometric Photoacoustic pH Imaging.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26418312.
- Also identified by DOI 10.1002/adma.201503194.
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Abstract
A photoacoustic nanoprobe is self-assembled from human serum albumin and two types of dye molecules, one is inert to pH and the other is pH sensitive. This probe and the quantitative ratiometric photoacoustic pH imaging method are shown to have high safety, be easy-to-operate, and have depth-independent accuracy for real-time in vivo pH imaging of entire tumors. These features make them promising for future cancer prognosis and therapeutic planning.
Medical subject headings
- Fluorescent Dyes
- Nanostructures
- Optical Imaging
- Photoacoustic Techniques
- Serum Albumin