Early, Real-Time Medical Diagnosis of Botulism by Endopeptidase-Mass Spectrometry.

Rosen, Osnat; Feldberg, Liron; Gura, Sigalit; Brosh-Nissimov, Tal; Guri, Alex; Zimhony, Oren; Shapiro, Eli; Beth-Din, Adi et al. · Clin Infect Dis · 2015

case_report · Level V

Where this comes from

Abstract

Botulinum toxin was detected in patient serum using Endopeptidase-mass-spectrometry assay, although all conventional tests provided negative results. Antitoxin was administered, resulting in patient improvement. Implementing this highly sensitive and rapid assay will improve preparedness for foodborne botulism and deliberate exposure.

Medical subject headings