Oral or intravenous iron for anemia correction in chronic kidney disease?
rct · Level II
Where this comes from
- Record sourced from PubMed, PMID 26422625.
- Also identified by DOI 10.1038/ki.2015.189.
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Abstract
Iron deficiency in patients with chronic kidney disease (CKD) can be corrected by the oral or intravenous route. The natural intestinal barrier against iron overload is circumvented by intravenous iron. The balance between benefit and risk of high iron doses remains unclear. In a randomized controlled trial in CKD patients, Agarwal et al. find similar effects of oral and intravenous iron on hemoglobin levels and kidney function decline but more serious cardiovascular events and infections with intravenous iron.
Medical subject headings
- Anemia, Iron-Deficiency
- Ferric Compounds
- Ferrous Compounds
- Glucaric Acid
- Hematinics
- Renal Insufficiency, Chronic