Fragility Fractures in Patients with Rheumatoid Arthritis and Osteoarthritis Compared with the General Population.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 26428208.
- Also identified by DOI 10.3899/jrheum.150325.
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Abstract
To determine the rate ratios of hip and distal radius fractures in patients with rheumatoid arthritis (RA), hip osteoarthritis (OA), and knee OA. Cohort study using healthcare data (1998-2012) covering the entire population of the Skåne region of Sweden. We found an increased rate of hip fracture in both female [standardized fracture rate ratio (SFR) 1.54, 95% CI 1.40-1.70] and male patients with RA (SFR 1.81, 95% CI 1.51-2.17). The hip fracture rate in female OA was reduced by 10-20%, and trochanteric fracture tended to have a higher rate ratio compared with the cervical. The 50-80% increased rate of hip fracture adds to the total burden of RA while the shifted distribution of cervical/trochanteric fractures in OA is in support of subchondral bone alterations.
Medical subject headings
- Arthritis, Rheumatoid
- Fractures, Spontaneous
- Hip Fractures
- Osteoarthritis
- Radius Fractures