Fat Chance for Neural Stem Cells in Alzheimer's Disease.

Gontier, Geraldine; Lin, Karin; Villeda, Saul A · Cell Stem Cell · 2015

editorial · Level V

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Abstract

Identifying factors driving neural stem cell dysfunction in age-related neurodegenerative diseases remains critical for the development of potential regenerative therapies. Now in Cell Stem Cell,Hamilton et al. (2015) find that lipid accumulation observed during early stages of Alzheimer's disease impairs neural stem cell activity in the adult brain.

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