Aortic and Mitral Valve Replacement Due to Extensive Inflammatory Immunoglobulin G4-Related Pseudotumor.

Besik, Josef; Pirk, Jan; Netuka, Ivan; Szarszoi, Ondrej; Marek, Tomas; Urban, Marian; Honsova, Eva; Laco, Jan · Ann Thorac Surg · 2015

case_report · Level V

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Abstract

A 64-year-old woman with extensive tumorous infiltration of the mitral and aortic valves underwent partial resection of a tumor of the left ventricular outflow tract and replacement of both affected valves. Histology revealed an inflammatory pseudotumor with a significant number of immunoglobulin-G4-positive plasma cells. The histologic and clinical findings suggested immunoglobulin-G4-related disease of the heart.

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