CARD9 mutation linked to Corynespora cassiicola infection in a Chinese patient.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 26440558.
- Also identified by DOI 10.1111/bjd.14082.
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Abstract
Corynespora cassiicola is a plant pathogen associated with leaf-spotting disease. The fungus has been found on diverse substrates: leaves, stems and roots of plants; nematode cysts and human skin. It rarely causes human infections. Here we report one case of subcutaneous phaeohyphomycosis caused by C. cassiicola with prominent tissue necrosis in a woman. All of her clinical features pointed towards a genetic linkage. Hence, whole-exome sequencing and Sanger sequencing were performed on this patient. One mutation of CARD9 was detected.
Medical subject headings
- Ascomycota
- CARD Signaling Adaptor Proteins
- Dermatomycoses
- Facial Dermatoses
- Mutation