Heterogeneity in Blood Product Acceptance Among Antenatal Patients of the Jehovah's Witness Faith.

Abstract

To understand the antepartum attitudes toward blood product transfusion among members of the Jehovah's Witness faith. We performed a retrospective study using antenatal consultation notes of Jehovah's Witness patients from the bloodless medicine program at a regional tertiary care maternity hospital over a 4-year period to determine their blood transfusion preferences. Eighty-seven consultations were performed. The median age of women undergoing consultation was 27 years (range 14-39 years), and most were either African American (48/87 [55.2%]; 95% confidence interval [CI] 44.8-65.7) or Caucasian (35/87 [40.2%]; 95% CI 29.9-50.5). The mean±standard deviation antenatal hemoglobin concentration was 11.9±1.4 g/dL (n=57). Although all 87 women stated that they would not accept conventional blood products such as red blood cells, plasma, or platelets, 55 of 87 (63.2%; 95% CI 53.1-73.3) stated that they would accept all of the recombinant or fractionated blood products including cryoprecipitate. Stated acceptance of fractionated or recombinant products did not vary by parity, race, or age. A further 23 of 87 (26.4%; 95% CI 17.1-35.7) women stated they would accept some but not all of the fractionated or recombinant blood products, whereas 9 of 87 (10.3%; 95% CI 3.9-16.7) stated they would not accept any of these products. In the antenatal period, Jehovah's Witness women have variable attitudes toward receipt of blood products. A discussion with each patient is essential to understand whether and which blood products may be used when indicated.