Impact of Regional Vein Thrombosis in Patients with Klebsiella pneumoniae Liver Abscess.
Where this comes from
- Record sourced from PubMed, PMID 26444702.
- Also identified by DOI 10.1371/journal.pone.0140129 and PMC identifier 4596830.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Klebsiella liver abscess (KLA) is an emerging infection in Asia caused by hypermucoviscous strains of Klebsiella pneumoniae. It is associated with thrombophlebitis of portal and hepatic veins. The natural history and role of anticoagulation for this regional thrombophlebitis is unclear. In a retrospective study of 169 subjects with KLA over 7 years, thrombophlebitis was identified in 53/169 (31.4%). Only 1 received therapeutic anticoagulation. Despite this 30/49 (73.2%) of those with follow up scan available showed improvement or recanalization (mean duration between scans 44 days). Abscess resolution was associated with improvement in thrombophlebitis.
Medical subject headings
- Klebsiella Infections
- Klebsiella pneumoniae
- Liver Abscess
- Thrombophlebitis