Spatially, Temporally, and Quantitatively Controlled Delivery of Broad Range of Molecules into Selected Cells through Plasmonic Nanotubes.

Messina, Gabriele C; Dipalo, Michele; La Rocca, Rosanna; Zilio, Pierfrancesco; Caprettini, Valeria; Proietti Zaccaria, Remo; Toma, Andrea; Tantussi, Francesco et al. · Adv Mater · 2015

basic_science · Level V

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Abstract

A Universal plasmonic/microfluidic platform for spatial and temporal controlled intracellular delivery is described. The system can inject/transfect the desired amount of molecules with an efficacy close to 100%. Moreover, it is highly scalable from single cells to large ensembles without administering the molecules to an extracellular bath. The latter enables quantitative control over the amount of injected molecules.

Medical subject headings