Differences in Metabolic Programming Define the Site of Breast Cancer Cell Metastasis.
Level V
Where this comes from
- Record sourced from PubMed, PMID 26445507.
- Also identified by DOI 10.1016/j.cmet.2015.09.022.
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Abstract
Although metabolic reprogramming is a hallmark of oncogenic transformation and growth of primary tumor cells, little is known about how metabolic alterations impact metastasis. In this issue of Cell Metabolism, Dupuy et al. (2015) show that primary breast cancer cells display metabolic heterogeneity, and that their distinct metabolic programs define their sites of metastasis.
Medical subject headings
- Breast Neoplasms
- Metabolic Engineering
- Protein Serine-Threonine Kinases