Carbon-Dot-Based Nanosensors for the Detection of Intracellular Redox State.

Liu, Ye; Tian, Ye; Tian, Yefei; Wang, Yajun; Yang, Wuli · Adv Mater · 2015

basic_science · Level V

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Abstract

Carbon-dot-based nanosensors are prepared through sequentially assembling a polymer/carbon dot multilayer shell on mesoporous silica nanoparticles with different crosslinking densities of disulfide bonds; they can be utilized to evaluate the gluthathione (GSH) concentration. In vitro cell assays demonstrate the feasibility of using such nanosensors in evaluating the intracellular redox state of different cells.

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