Adrenergic Fight-or-Flight: S-NO Falls on PKA Targets.

Bers, Donald M · Circ Res · 2015

editorial · Level V

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Abstract

In this issue of <i>Circulation Research</i>, Irie <i>et al</i>. demonstrate novel aspects of crosstalk downstream of β-adrenergic receptor (β-AR) between classical cAMP-dependent protein kinase (PKA) target proteins and nitric oxide synthase (NOS) signaling in cardiac myocytes. This study opens up intriguing new questions for this field.

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