"A Sledgehammer Breaks Glass but Forges Steel": Bacteria Adhesion Shapes Gut Immunity.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 26451476.
- Also identified by DOI 10.1016/j.cell.2015.09.040.
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Abstract
Gut bacteria are known to affect immune cell development, but most intestinal lymphocytes have no direct contact with luminal bacteria. Two studies by Atarashi et al. and Sano et al. shed light on how bacterial adhesion can cue intestinal epithelial cells to direct differentiation of gut T cells.
Medical subject headings
- Bacterial Adhesion
- Citrobacter rodentium
- Enterobacteriaceae Infections
- Escherichia coli Infections
- Escherichia coli O157
- Gastrointestinal Microbiome
- Interleukins
- Intestinal Mucosa
- Intestines
- Receptors, Interleukin
- Serum Amyloid A Protein
- Th17 Cells