Empirical Estimation of R0 for Unknown Transmission Functions: The Case of Chronic Wasting Disease in Alberta.
Where this comes from
- Record sourced from PubMed, PMID 26452231.
- Also identified by DOI 10.1371/journal.pone.0140024 and PMC identifier 4599850.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
We consider the problem of estimating the basic reproduction number R0 from data on prevalence dynamics at the beginning of a disease outbreak. We derive discrete and continuous time models, some coefficients of which are to be fitted from data. We show that prevalence of the disease is sufficient to determine R0. We apply this method to chronic wasting disease spread in Alberta determining a range of possible R0 and their sensitivity to the probability of deer annual survival.
Medical subject headings
- Basic Reproduction Number
- Empirical Research
- Wasting Disease, Chronic