Immediate Adjuvant Radiation Therapy Following Radical Prostatectomy Should Not Be Advised for Men with Extraprostatic Extension Who Have Negative Surgical Margins.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 26470628.
- Also identified by DOI 10.1016/j.eururo.2015.09.045.
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Abstract
Although three large randomized prospective clinical trials have demonstrated that postoperative radiotherapy in patients with adverse pathological features reduces prostate-specific antigen recurrence and may decrease clinical failure, this approach has not gained widespread acceptance, likely because the data strongly support such an approach only in men with Gleason ≥7 with positive surgical margins.
Medical subject headings
- Patient Selection
- Prostatic Neoplasms