Much ado about zero.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26496595.
- Also identified by DOI 10.1016/j.cell.2015.10.033.
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Abstract
LINE retrotransposons actively shape mammalian genomes. Denli et al. reveal a new open reading frame, ORF0, on the antisense strand of human LINE-1 encoding a small regulatory protein. This finding may represent the birth of an emerging retrotransposon gene that can adopt various fates, as it can be fused to adjacent host sequences.
Medical subject headings
- Pan troglodytes
- Retroelements