HIV-1 Reservoir Association with Immune Activation.
cross_sectional · Level IV
Where this comes from
- Record sourced from PubMed, PMID 26501094.
- Also identified by DOI 10.1016/j.ebiom.2015.08.025 and PMC identifier 4588428.
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Abstract
In this issue of EBioMedicine, Ruggiero and colleagues describe immune activation biomarkers associated with the size of the HIV reservoir in a carefully designed cross-sectional study. The cohort consists of a homogeneous sample of HIV-1-infected patients with long-term plasma HIV-1 RNA suppression under antiretroviral treatment (ART). It is crucial to explore the potential utility of biomarkers that are easier (less labor intensive, less expensive) to measure than integrated HIV DNA load, in order to quickly and accurately quantify cellular reservoirs of HIV.
Medical subject headings
- HIV-1
- Viral Load