IsoMIF Finder: online detection of binding site molecular interaction field similarities.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26504139.
- Also identified by DOI 10.1093/bioinformatics/btv616 and PMC identifier 4743630.
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Abstract
IsoMIF Finder is an online server for the identification of molecular interaction field (MIF) similarities. User defined binding site MIFs can be compared to datasets of pre-calculated MIFs or against a user-defined list of PDB entries. The interface can be used for the prediction of function, identification of potential cross-reactivity or polypharmacological targets and drug repurposing. Detected similarities can be viewed in a browser or within a PyMOL session. IsoMIF Finder uses JSMOL (no java plugin required), is cross-browser and freely available at bcb.med.usherbrooke.ca/imfi.
Medical subject headings
- Pharmaceutical Preparations
- Proteins
- Software