Right-Sizing Adjuvant and Neoadjuvant Clinical Trials in Breast Cancer.
expert_opinion · Level V
Where this comes from
- Record sourced from PubMed, PMID 26510857.
- Also identified by DOI 10.1158/1078-0432.CCR-15-1903 and PMC identifier 4703523.
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Abstract
I describe a simple and intuitive method for finding sample size for clinical trials in primary breast cancer based on neoadjuvant trial results and using the FDA's patient-level meta-analysis. Then I explain a problem with this method and how the problem can be remedied.
Medical subject headings
- Breast Neoplasms
- Neoadjuvant Therapy