A histamine-independent itch pathway is required for allergic ocular itch.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 26521042.
- Also identified by DOI 10.1016/j.jaci.2015.08.047 and PMC identifier 4826842.
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Abstract
Non-histaminergic TRPA1 neural pathway is required for the development of allergic ocular itch. Pharmacological inhibition of TRPA1 channel can lead to novel therapeutic strategies to treat ocular itch in severe allergic conjunctivitis.
Medical subject headings
- Conjunctivitis, Allergic
- Histamine
- Pruritus
- TRPV Cation Channels
- Transient Receptor Potential Channels