Resident Memory T Cells as Surrogate Markers of the Efficacy of Cancer Vaccines.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26542056.
- Also identified by DOI 10.1158/1078-0432.CCR-15-2364.
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Abstract
Cancer vaccine boost via the cervicovaginal rather than the intramuscular route of immunization appears to be crucial to induce genital CD8(+) T cells and tumor regression. This clinical activity is correlated with the ability of the mucosal boost to elicit resident memory T cells in the genital tract.
Medical subject headings
- CD8-Positive T-Lymphocytes
- Cancer Vaccines