Three, two, one… TROPHO-BLAST OFF!
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 26544108.
- Also identified by DOI 10.1016/j.stem.2015.10.005.
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Abstract
Trophoblast stem cells (TSCs) are derived from the early mouse embryo and can substantially contribute to placental development. Two studies by Kubaczka et al. (2015) and Benchetrit et al. (2015) in this issue of Cell Stem Cell now report reprogramming mouse fibroblasts into TSCs, surmounting the first lineage barrier established in development and providing new tools for researching placental specification and diseases.
Medical subject headings
- Stem Cells
- Trophoblasts