Histone Marks Direct Chromosome Segregation.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26544931.
- Also identified by DOI 10.1016/j.cell.2015.10.043.
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Abstract
Germline stem cells divide asymmetrically, producing a self-renewing stem cell and a differentiating progenitor. Xie et al. now show that this depends on two asymmetric events that together partition a genome copy, carrying the old histones to the stem cell daughter and a copy with new, unmarked histones to the differentiating daughter.
Medical subject headings
- Drosophila Proteins
- Drosophila melanogaster
- Histones
- Spermatogenesis