Acquired Resistance to Bedaquiline and Delamanid in Therapy for Tuberculosis.
case_report · Level V
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- Record sourced from PubMed, PMID 26559594.
- Also identified by DOI 10.1056/NEJMc1505196 and PMC identifier 4681277.
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Abstract
Treatment of multidrug-resistant Mycobacterium tuberculosis is a challenge. This letter describes the emergence of resistance to new therapies, bedaquiline and delamanid.
Medical subject headings
- Antitubercular Agents
- Diarylquinolines
- Drug Resistance, Bacterial
- Mutation
- Mycobacterium tuberculosis
- Nitroimidazoles
- Oxazoles
- Tuberculosis, Multidrug-Resistant