The Role of Echinocandins in Candida Biofilm-Related Vascular Catheter Infections: In Vitro and In Vivo Model Systems.

Ghannoum, Mahmoud; Roilides, Emmanuel; Katragkou, Aspasia; Petraitis, Vidmantas; Walsh, Thomas J · Clin Infect Dis · 2015

basic_science · Level V

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Abstract

Candida biofilm-associated infections of central venous catheters are a challenging therapeutic problem. Recent in vitro and in vivo studies of the structure, formation, pathogenesis, and treatment establish a rationale for new approaches to management of these tenacious infections.

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