Pathological-Condition-Driven Construction of Supramolecular Nanoassemblies for Bacterial Infection Detection.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26568542.
- Also identified by DOI 10.1002/adma.201503437.
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Abstract
A pyropheophorbide-α-based building block (Ppa-PLGVRG-Van) can be used to construct self-aggregated superstructures in vivo for highly specific and sensitive diagnosis of bacterial infection by noninvasive photoacoustic tomography. This in vivo supramolecular chemistry approach opens a new avenue for efficient, rapid, and early-stage disease diagnosis with high sensitivity and specificity.
Medical subject headings
- Bacterial Infections
- Chlorophyll
- Contrast Media
- Nanostructures
- Photoacoustic Techniques
- Tomography
- Vancomycin