MIEC-SVM: automated pipeline for protein peptide/ligand interaction prediction.

Li, Nan; Ainsworth, Richard I; Wu, Meixin; Ding, Bo; Wang, Wei · Bioinformatics · 2016

basic_science · Level V

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Abstract

MIEC-SVM is a structure-based method for predicting protein recognition specificity. Here, we present an automated MIEC-SVM pipeline providing an integrated and user-friendly workflow for construction and application of the MIEC-SVM models. This pipeline can handle standard amino acids and those with post-translational modifications (PTMs) or small molecules. Moreover, multi-threading and support to Sun Grid Engine (SGE) are implemented to significantly boost the computational efficiency. The program is available at http://wanglab.ucsd.edu/MIEC-SVM CONTACT: : wei-wang@ucsd.edu Supplementary data available at Bioinformatics online.

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