Pharmacogenomic agreement between two cancer cell line data sets.
basic_science · Level V
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- Record sourced from PubMed, PMID 26570998.
- Also identified by DOI 10.1038/nature15736 and PMC identifier PMC3721163.
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Abstract
Large cancer cell line collections broadly capture the genomic diversity of human cancers and provide valuable insight into anti-cancer drug response. Here we show substantial agreement and biological consilience between drug sensitivity measurements and their associated genomic predictors from two publicly available large-scale pharmacogenomics resources: The Cancer Cell Line Encyclopedia and the Genomics of Drug Sensitivity in Cancer databases.