Multifunctional Silica Nanoparticles for Covalent Immobilization of Highly Sensitive Proteins.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26572079.
- Also identified by DOI 10.1002/adma.201503935.
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Abstract
A convenient reverse micellar one-pot reaction yields multifunctional silica nanoparticles, which can be tailored to effectively suppress non-specific adsorption and, at the same time, enable efficient specific covalent immobilization of proteins. Using two highly sensitive proteins, it is demonstrated that the new particles provide a suitable microenvironment to maintain the protein's activity.
Medical subject headings
- Immobilized Proteins
- Nanoparticles
- Silicon Dioxide