JSpeciesWS: a web server for prokaryotic species circumscription based on pairwise genome comparison.
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Where this comes from
- Record sourced from PubMed, PMID 26576653.
- Also identified by DOI 10.1093/bioinformatics/btv681 and PMC identifier 5939971.
- Licence recorded as CC BY-NC.
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Abstract
JSpecies Web Server (JSpeciesWS) is a user-friendly online service for in silico calculating the extent of identity between two genomes, a parameter routinely used in the process of polyphasic microbial species circumscription. The service measures the average nucleotide identity (ANI) based on BLAST+ (ANIb) and MUMmer (ANIm), as well as correlation indexes of tetra-nucleotide signatures (Tetra). In addition, it provides a Tetra Correlation Search function, which allows to rapidly compare selected genomes against a continuously updated reference database with currently about 32 000 published whole and draft genome sequences. For comparison, own genomes can be uploaded and references can be selected from the JSpeciesWS reference database. The service indicates whether two genomes share genomic identities above or below the species embracing thresholds, and serves as a fast way to allocate unknown genomes in the frame of the hitherto sequenced species. JSpeciesWS is available at http://jspecies.ribohost.com/jspeciesws Supplementary data are available at Bioinformatics online. mrichter@ribocon.com.
Medical subject headings
- Genome
- Prokaryotic Cells