A coherent transcriptional feed-forward motif model for mediating auxin-sensitive PIN3 expression during lateral root development.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26578065.
- Also identified by DOI 10.1038/ncomms9821 and PMC identifier 4673502.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Multiple plant developmental processes, such as lateral root development, depend on auxin distribution patterns that are in part generated by the PIN-formed family of auxin-efflux transporters. Here we propose that AUXIN RESPONSE FACTOR7 (ARF7) and the ARF7-regulated FOUR LIPS/MYB124 (FLP) transcription factors jointly form a coherent feed-forward motif that mediates the auxin-responsive PIN3 transcription in planta to steer the early steps of lateral root formation. This regulatory mechanism might endow the PIN3 circuitry with a temporal 'memory' of auxin stimuli, potentially maintaining and enhancing the robustness of the auxin flux directionality during lateral root development. The cooperative action between canonical auxin signalling and other transcription factors might constitute a general mechanism by which transcriptional auxin-sensitivity can be regulated at a tissue-specific level.
Medical subject headings
- Arabidopsis
- Arabidopsis Proteins
- Gene Expression Regulation, Plant
- Plant Roots
- RNA, Messenger
- Transcription Factors