Uromodulin, kidney function, cardiovascular disease, and mortality.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 26579681.
- Also identified by DOI 10.1038/ki.2015.267.
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Abstract
Uromodulin (Tamm-Horsfall protein) is exclusively produced by the kidney and is the most abundant protein excreted in normal urine. The level of uromodulin in urine could represent a useful biomarker for renal tubular function. The study of Garimella et al. adds elements into the debate, by suggesting that, in elderly adults, low urinary uromodulin concentrations in spot urine identify people at risk of progressive kidney disease and mortality above and beyond established markers of kidney disease.
Medical subject headings
- Kidney Diseases
- Uromodulin