Microbiota's No Wasting Policy.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26590415.
- Also identified by DOI 10.1016/j.cell.2015.10.077.
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Abstract
Schieber et al. demonstrate that a specific gut microbiota bacterial strain induces a host-mediated protection mechanism against inflammation-driven wasting syndrome. This salutary effect confers a net survival advantage against bacterial infection, without interfering with the host's pathogen load, revealing that host-microbiota interactions regulate disease tolerance to infection.
Medical subject headings
- Escherichia coli
- Inflammasomes
- Insulin-Like Growth Factor I
- Intestines
- Microbiota
- Muscle, Skeletal
- Wasting Syndrome