Scanning proton beam therapy reduces normal tissue exposure in pelvic radiotherapy for anal cancer.

Anand, Aman; Bues, Martin; Rule, William G; Keole, Sameer R; Beltran, Chris J; Yin, Jun; Haddock, Michael G; Hallemeier, Christopher L et al. · Radiother Oncol · 2015

other · Level V

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Abstract

An inter-comparison planning study between photon beam therapy (IMRT) and scanning proton beam therapy (SPBT) for squamous cell carcinoma of the anus (SCCA) is presented. SPBT plans offer significant reduction (>50%, P=0.008) in doses to small bowel, and bone marrow thereby offering the potential to reduce bowel and hemotoxicities.

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