Sertraline-Associated Cholestasis and Ductopenia Consistent with Vanishing Bile Duct Syndrome.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 26597434.
- Also identified by DOI 10.1016/j.jpeds.2015.10.065.
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Abstract
An adolescent with depression treated with sertraline developed cholestasis and bile duct paucity, which resolved with medication discontinuation. Vanishing bile duct syndrome is an acquired destruction of interlobular bile ducts. This type of drug-induced liver injury has been associated with other medications and requires practitioners' awareness of potential hepatotoxicity.
Medical subject headings
- Antidepressive Agents
- Bile Ducts, Intrahepatic
- Chemical and Drug Induced Liver Injury
- Cholestasis
- Sertraline