Degradable Magnetic Composites for Minimally Invasive Interventions: Device Fabrication, Targeted Drug Delivery, and Cytotoxicity Tests.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26603856.
- Also identified by DOI 10.1002/adma.201503112.
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Abstract
Superparamagnetic nanoparticles and a functional, degradable polymer matrix based on poly(ethylene glycol) are combined to enable fully degradable magnetic microdevices for minimally invasive biomedical applications. A bioinspired helical microrobot platform mimicking Escherichia coli bacteria is fabricated and actuated using weak rotating magnetic fields. Locomotion based on corkscrew propulsion, targeted drug delivery, and low-degradation-product cytotoxicity are demonstrated.
Medical subject headings
- Acrylates
- Drug Carriers
- Magnets
- Materials Testing
- Polyethylene Glycols
- Propylene Glycols
- Robotics