The Acute to Chronic Pain Transition: Can Chronic Pain Be Prevented?
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 26614716.
- Also identified by DOI 10.1016/j.mcna.2015.08.005.
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Abstract
Chronic postsurgical pain (CPSP) is a distressing disease process that can lead to long-term disability, reduced quality of life, and increased health care spending. Although the exact mechanism of development of CPSP is unknown, nerve injury and inflammation may lead to peripheral and central sensitization. Given the complexity of the disease process, no novel treatment has been identified. The preoperative use of multimodal analgesia has been shown to decrease acute postoperative pain, but it has no proven efficacy in preventing development of CPSP.
Medical subject headings
- Acute Pain
- Chronic Pain
- Combined Modality Therapy
- Pain Management
- Postoperative Pain