Admix'em: a flexible framework for forward-time simulations of hybrid populations with selection and mate choice.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26615212.
- Also identified by DOI 10.1093/bioinformatics/btv700.
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Abstract
We introduce a new forward-time simulator, Admix'em, that allows for rapid and realistic simulations of admixed populations with selection. Complex selection can be achieved through user-defined fitness and mating-preference probability functions. Users can specify realistic genomic landscapes and model neutral SNPs in addition to sites under selection. Admix'em is designed to simulate selection in admixed populations but can also be used as a general population simulator. Usage and examples are in the supplement. C ++ and OpenMP, supports 64-bit Linux/Unix-like platforms. https://github.com/melop/admixem rcui@age.mpg.de Supplementary data are available at Bioinformatics online.
Medical subject headings
- Genomics
- Polymorphism, Single Nucleotide