Multifunctional Nanostructures for Tumor-Targeted Molecular Imaging and Photodynamic Therapy.

Wu, Hao; Wang, Huihui; Liao, Han; Lv, Yan; Song, Xiaojie; Ma, Xiaojun; Tan, Mingqian · Adv Healthc Mater · 2016

basic_science · Level V

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Abstract

A multifunctional ICG-FA-PPD nanostructure is constructed by a facile self-assembly method through the negatively charged indocyanine green (ICG)- and positively charged folic acid-modified PEI-PEG-gadoteric acid (FA-PPD). The resulting ICG-FA-PPD is not only able to be used for targeting tumors, magnetic resonance imaging (MRI), and near-infrared imaging, but, more importantly, it enables photodynamic therapy for tumor.

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