More Frequent than Desired: Midgut Stem Cell Somatic Mutations.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26637937.
- Also identified by DOI 10.1016/j.stem.2015.11.011.
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Abstract
The accumulation of somatic mutations in adult stem cells contributes to the decline of tissue functions and cancer initiation. In this issue of Cell Stem Cell, Siudeja et al. (2015) investigate the rate and mechanism of naturally occurring mutations in Drosophila midgut intestinal stem cells during aging and find high-frequency mutations arising from multiple mechanisms.
Medical subject headings
- Adult Stem Cells
- Drosophila