Photocleavable Hydrogels for Light-Triggered siRNA Release.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26639103.
- Also identified by DOI 10.1002/adhm.201500778 and PMC identifier 4755586.
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Abstract
A photocleavable hydrogel system for on-demand delivery of genetic material is reported. The release of short interfering RNAs can be triggered by the application of UV light without any loss in bioactivity. This approach provides a promising external stimulus-based nucleic acid delivery platform for applications in disease therapeutics and tissue regeneration.
Medical subject headings
- Hydrogels
- RNA, Small Interfering