Dietary Iron Oxide Nanoparticles Delay Aging and Ameliorate Neurodegeneration in Drosophila.

Zhang, Yi; Wang, Zhuyao; Li, Xiaojiao; Wang, Lu; Yin, Min; Wang, Lihua; Chen, Nan; Fan, Chunhai et al. · Adv Mater · 2016

basic_science · Level V

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Abstract

Dietary iron oxide nanoparticles are shown to ameliorate neurodegeneration in a Drosophelia Alzheimer's disease model. Iron oxide nanoparticles can mimic catalase and can decompose reactive oxygen species (ROS). This has potential therapeutic uses for aging, metabolic disorders, and neurodegenerative diseases, in which increased production of ROS is closely implicated.

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