CCR 20th Anniversary Commentary: Autologous T Cells-The Ultimate Personalized Drug for the Immunotherapy of Human Cancer.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 26672082.
- Also identified by DOI 10.1158/1078-0432.CCR-14-3131 and PMC identifier 4683397.
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Abstract
The article by Rosenberg and colleagues, which was published in the July 1, 2011, issue of Clinical Cancer Research, demonstrated the power of the adoptive transfer of autologous antitumor T cells to mediate the complete, durable, and likely curative regression of cancer in patients with heavily pretreated metastatic melanoma. It also provided a stimulus to the development of cell transfer approaches for other cancer types using both natural and genetically engineered lymphocytes.
Medical subject headings
- Immunotherapy, Adoptive
- Neoplasms
- Precision Medicine
- T-Lymphocytes