Defining the Risk of Small Polyps: Potential Value of CTC.

Abstract

Although the clinical importance of large colorectal polyps and the benign nature of diminutive polyps are generally accepted, elucidating the clinical significance of small polyps (6-9 mm) could have an enormous impact on colorectal cancer (CRC) screening. Serial volumetric measurement via CTC may be a valuable method for assessing changes in polyp size. With the recognition of alternative CRC pathways, a more precise understanding of the natural history of small colorectal polyps is needed and data such as those reported by Nolthenius contribute to that knowledge.